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Multiple Choice
In cellular respiration, which stage produces the most ATP in aerobic eukaryotic cells?
A
Pyruvate oxidation (conversion of pyruvate to acetyl-CoA)
B
Glycolysis
C
Oxidative phosphorylation (electron transport chain and chemiosmosis)
D
Citric acid cycle (Krebs cycle)
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Verified step by step guidance
1
Identify the main stages of aerobic cellular respiration: Glycolysis, Pyruvate Oxidation, Citric Acid Cycle (Krebs Cycle), and Oxidative Phosphorylation (Electron Transport Chain and Chemiosmosis).
Understand the ATP yield from each stage: Glycolysis produces a small amount of ATP directly, Pyruvate Oxidation does not produce ATP directly but generates electron carriers, the Citric Acid Cycle produces some ATP and electron carriers, and Oxidative Phosphorylation uses these electron carriers to generate a large amount of ATP.
Recall that Oxidative Phosphorylation involves the electron transport chain creating a proton gradient across the mitochondrial membrane, which drives ATP synthesis via chemiosmosis.
Recognize that the majority of ATP in aerobic respiration is produced during Oxidative Phosphorylation because it harnesses the energy from NADH and FADH2 generated in previous stages to produce ATP efficiently.
Conclude that among the listed stages, Oxidative Phosphorylation produces the most ATP in aerobic eukaryotic cells.