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Multiple Choice
Specific substrates bind to which of the following parts of an enzyme?
A
Allosteric site
B
Regulatory domain
C
Cofactor binding site
D
Active site
Verified step by step guidance
1
Understand the role of an enzyme: Enzymes are biological catalysts that speed up chemical reactions by lowering the activation energy. They achieve this by binding to specific substrates.
Learn about the active site: The active site is the region of the enzyme where the substrate binds. It has a specific shape and chemical properties that match the substrate, allowing for a precise fit (often described as a 'lock and key' model or 'induced fit' model).
Differentiate the active site from other parts of the enzyme: The allosteric site is a separate region where molecules can bind to regulate enzyme activity, but it does not directly bind the substrate. The regulatory domain and cofactor binding site are also distinct regions that serve other functions, such as modulating activity or binding non-protein molecules required for enzyme function.
Recognize the specificity of substrate binding: Substrates bind to the active site due to complementary shape, charge, and hydrophobic/hydrophilic interactions. This specificity ensures that enzymes catalyze only particular reactions.
Conclude that the correct answer is the active site: Based on the explanation above, the active site is the part of the enzyme where specific substrates bind to undergo a chemical reaction.