Multiple Choice
The special shape on an enzyme where the substrate binds to it is the _____.
20
views
6. Enzymes and Enzyme Kinetics
Enzyme-Substrate Complex
Struggling with Biochemistry?
Join thousands of students who trust us to help them ace their exams!Watch the first videoMultiple Choice
Which enzyme covalently links nucleotides together during the formation of a nucleic acid strand?
A
Topoisomerase
B
Primase
C
Helicase
D
DNA ligase
Verified step by step guidance1
Understand the role of each enzyme listed in the problem: Topoisomerase relieves supercoiling in DNA during replication, Primase synthesizes short RNA primers to initiate DNA synthesis, Helicase unwinds the DNA double helix, and DNA ligase covalently links nucleotides together by forming phosphodiester bonds.
Recall that DNA ligase is specifically responsible for sealing nicks in the sugar-phosphate backbone of DNA, which occurs during replication or repair processes.
Recognize that DNA ligase catalyzes the formation of a phosphodiester bond between the 3'-hydroxyl group of one nucleotide and the 5'-phosphate group of another nucleotide.
Understand that this process is essential for joining Okazaki fragments on the lagging strand during DNA replication and for repairing breaks in the DNA strand.
Conclude that DNA ligase is the correct enzyme responsible for covalently linking nucleotides together during the formation of a nucleic acid strand.
3:14mWatch next
Master Enzyme-Substrate Complex with a bite sized video explanation from Jason
Start learningRelated Videos
Related Practice
Enzyme-Substrate Complex practice set
Problem sets built by lead tutorsExpert video explanations