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Multiple Choice
Which groups of amino acids are covalently linked to form the primary structure of a protein?
A
R groups (side chains)
B
Amino and carboxyl groups
C
Phosphate groups
D
Hydroxyl groups
Verified step by step guidance
1
Understand the primary structure of a protein: The primary structure refers to the linear sequence of amino acids in a polypeptide chain, linked by covalent bonds.
Recognize the type of covalent bond involved: Amino acids are linked together by peptide bonds, which are formed between the amino group (-NH₂) of one amino acid and the carboxyl group (-COOH) of another.
Clarify the role of R groups (side chains): R groups are not directly involved in forming the peptide bonds that create the primary structure. They contribute to the chemical properties and interactions of the amino acids but are not part of the covalent linkage in the primary structure.
Exclude other groups: Phosphate groups and hydroxyl groups are not involved in forming the primary structure of proteins. These groups may play roles in other biochemical processes or structures, but they are not part of the covalent linkage in the primary structure.
Summarize the correct answer: The primary structure of a protein is formed by covalent bonds between the amino group (-NH₂) and the carboxyl group (-COOH) of adjacent amino acids, creating a peptide bond.