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Multiple Choice
In oxidative phosphorylation, what is the primary purpose of NADH and FADH2?
A
To directly catalyze the phosphorylation of ADP to ATP in the cytosol
B
To serve as the terminal electron acceptor by combining with electrons to form water
C
To transport fatty acids into the mitochondrial matrix for beta-oxidation
D
To donate high-energy electrons to the electron transport chain, helping drive proton pumping and ATP synthesis
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Verified step by step guidance
1
Understand the role of NADH and FADH2 in cellular respiration, specifically in oxidative phosphorylation.
Recognize that NADH and FADH2 are electron carriers that carry high-energy electrons derived from metabolic pathways like the Krebs cycle.
Know that these electrons are donated to the electron transport chain (ETC) located in the inner mitochondrial membrane.
Realize that the flow of electrons through the ETC drives proton pumping across the membrane, creating a proton gradient.
Understand that this proton gradient powers ATP synthase to produce ATP from ADP and inorganic phosphate, linking the electron donation by NADH and FADH2 to ATP synthesis.