Multiple Choice
In oxidative phosphorylation, what is the primary role of NADH in cellular respiration?
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Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation
Oxidative Phosphorylation 1
Multiple Choice
In oxidative phosphorylation, what is the primary role of NADH in cellular respiration?
A
Accepts electrons from Complex IV to form water as the terminal electron acceptor
B
Donates high-energy electrons to Complex I of the electron transport chain, helping drive proton pumping across the inner mitochondrial membrane
C
Directly phosphorylates ADP to ATP by transferring a phosphate group to ADP in the mitochondrial matrix
D
Transports pyruvate from the cytosol into the mitochondrial matrix for entry into the citric acid cycle
Verified step by step guidance1
Understand the role of NADH in cellular respiration, specifically in the context of oxidative phosphorylation, which occurs in the mitochondria.
Recall that NADH is a high-energy electron carrier produced during glycolysis, the citric acid cycle, and other metabolic pathways.
Identify that NADH donates electrons to the electron transport chain (ETC), specifically to Complex I, initiating the process of electron transfer through the chain.
Recognize that the electrons donated by NADH to Complex I help drive proton pumping from the mitochondrial matrix to the intermembrane space, creating a proton gradient across the inner mitochondrial membrane.
Understand that this proton gradient is then used by ATP synthase to produce ATP, but NADH itself does not directly phosphorylate ADP or transport pyruvate.
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