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Multiple Choice
In aerobic cells, what are the net products of glycolysis per 1 molecule of glucose?
A
1 pyruvate, 4 ATP (net), and 2 NADH
B
2 pyruvate, 2 ATP (net), 2 NADH, and 2 H
C
2 lactate, 2 ATP (net), and 2 NAD
D
2 acetyl-CoA, 2 ATP (net), and 2 NADH
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Verified step by step guidance
1
Recall that glycolysis is the metabolic pathway that breaks down one molecule of glucose (a 6-carbon sugar) into two molecules of pyruvate (each with 3 carbons).
Identify the net ATP production: Although 4 ATP molecules are produced during glycolysis, 2 ATP molecules are consumed in the early steps, resulting in a net gain of 2 ATP per glucose molecule.
Determine the NADH production: During the oxidation steps of glycolysis, 2 molecules of NAD+ are reduced to 2 molecules of NADH per glucose molecule.
Note that glycolysis produces 2 pyruvate molecules per glucose, not 1 pyruvate or lactate (which is produced under anaerobic conditions).
Understand that water (H\_2O) is also produced during glycolysis as a byproduct, but acetyl-CoA is formed later in the mitochondria after glycolysis, not during glycolysis itself.