Multiple Choice
Where does glycolysis primarily take place in a eukaryotic cell?
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Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway
Glycolysis 1
Multiple Choice
In aerobic glycolysis starting from one molecule of glucose, what is the net gain of ATP produced directly by substrate-level phosphorylation?
A
ATP
B
ATP
C
ATP
D
ATP
Verified step by step guidance1
Identify the stages of aerobic glycolysis where substrate-level phosphorylation occurs. These are the steps in glycolysis that directly produce ATP without involving the electron transport chain.
Recall that glycolysis converts one molecule of glucose into two molecules of pyruvate, producing ATP in two key steps: the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate and the conversion of phosphoenolpyruvate to pyruvate.
Note that each of these steps produces ATP, and since two molecules of glyceraldehyde-3-phosphate are formed per glucose, the ATP produced in these steps is doubled.
Calculate the total ATP produced by substrate-level phosphorylation by summing the ATP molecules generated in these steps and subtracting the ATP invested at the beginning of glycolysis (which is 2 ATP).
Express the net ATP gain from substrate-level phosphorylation during glycolysis as: \(\text{Net ATP} = (4 \text{ ATP produced}) - (2 \text{ ATP consumed})\).
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