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Multiple Choice
Which of the following statements regarding signal transduction pathways in cells is FALSE?
A
A ligand, such as a hormone, binds to a specific cell surface receptor on a target cell.
B
Signal transduction cascades, often involving protein kinases, amplify a signal intracellularly.
C
A receptor changes conformation upon ligand binding, transmitting a signal across the cell membrane.
D
Signal transduction cascades directly transmit a single stimulus to one, single target, identically in all cells.
E
Phosphatases remove phosphoryl groups from polypeptides, regulating a cell's response.
Verified step by step guidance
1
Understand the concept of signal transduction: Signal transduction is the process by which a cell converts an extracellular signal into a response. This often involves a series of molecular events, including the activation of proteins and other molecules.
Identify the role of ligands and receptors: Ligands, such as hormones, bind to specific receptors on the cell surface. This binding typically causes the receptor to change shape, initiating the signal transduction process.
Explore the function of protein kinases: Protein kinases are enzymes that modify other proteins by chemically adding phosphate groups. This phosphorylation can activate or deactivate proteins, thus amplifying the signal within the cell.
Examine the role of phosphatases: Phosphatases are enzymes that remove phosphate groups from proteins. This action can reverse the effects of kinases, thus playing a crucial role in regulating the cell's response to signals.
Analyze the false statement: The statement that signal transduction cascades directly transmit a single stimulus to one, single target, identically in all cells is false. Signal transduction pathways are complex and can lead to different responses in different cell types, depending on the specific proteins and pathways involved.