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Multiple Choice
Which hormone from the plot below shows the highest binding affinity for the receptor?
A
Hormone X.
B
Hormone Y.
C
Hormone Z.
Verified step by step guidance
1
Understand that binding affinity refers to the strength of the interaction between a ligand (such as a hormone) and its receptor. A higher binding affinity means that a lower concentration of the ligand is needed to achieve a certain level of receptor activation.
Examine the plot, which shows the percentage of active receptors on the y-axis and the concentration of ligand on the x-axis. The x-axis is on a logarithmic scale, which is common for these types of plots.
Identify the curves for Hormone X, Hormone Y, and Hormone Z. Each curve represents the relationship between ligand concentration and receptor activation for one of the hormones.
Determine which hormone has the highest binding affinity by finding the curve that reaches a given percentage of active receptors (e.g., 50%) at the lowest ligand concentration. This is because a lower concentration needed for activation indicates a higher affinity.
Observe that Hormone X reaches a higher percentage of active receptors at a lower ligand concentration compared to Hormones Y and Z, indicating that Hormone X has the highest binding affinity for the receptor.