Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

4. Protein Structure

Tertiary Structure of Protein

Biochemistry

4. Protein Structure

Tertiary Structure of Protein

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Multiple Choice

Which of the following interactions primarily stabilize the tertiary structure of a protein?

Only peptide bonds

Phosphodiester bonds

Hydrogen bonds, disulfide bridges, hydrophobic interactions, and ionic bonds

Glycosidic linkages

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Verified step by step guidance

Understand the concept of tertiary structure: The tertiary structure of a protein refers to its three-dimensional shape, which is stabilized by various interactions between the side chains (R groups) of amino acids.

Identify the types of interactions involved: Tertiary structure is primarily stabilized by hydrogen bonds, disulfide bridges, hydrophobic interactions, and ionic bonds. These interactions occur between the side chains of amino acids and contribute to the protein's overall stability.

Clarify why peptide bonds are not the primary stabilizers: Peptide bonds are covalent bonds that link amino acids together in the primary structure of a protein. While they are essential for forming the protein backbone, they do not play a direct role in stabilizing the tertiary structure.

Explain why phosphodiester bonds and glycosidic linkages are irrelevant: Phosphodiester bonds are found in nucleic acids (DNA and RNA), and glycosidic linkages are found in carbohydrates. Neither of these bond types is involved in protein tertiary structure stabilization.

Summarize the correct answer: The primary stabilizing interactions for the tertiary structure of a protein are hydrogen bonds, disulfide bridges, hydrophobic interactions, and ionic bonds. These interactions ensure the protein folds into its functional three-dimensional shape.