Multiple Choice
In aerobic metabolism of one molecule of glucose in a eukaryotic cell, which pathway produces the greatest amount of ATP (directly and/or via NADH/FADH delivered to the electron transport chain)?
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Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation
Oxidative Phosphorylation 1
Multiple Choice
In aerobic cellular respiration, which metabolic pathway produces the greatest amount of ATP per molecule of glucose?
A
Citric acid (TCA) cycle
B
Oxidative phosphorylation via the electron transport chain
C
Glycolysis
D
Fermentation
Verified step by step guidance1
Step 1: Understand the main metabolic pathways involved in aerobic cellular respiration: Glycolysis, Citric acid (TCA) cycle, and Oxidative phosphorylation via the electron transport chain.
Step 2: Recall the ATP yield from each pathway per molecule of glucose: Glycolysis produces a small amount of ATP directly, the Citric acid cycle produces some ATP and electron carriers, and Oxidative phosphorylation produces ATP by using the electron carriers generated in previous steps.
Step 3: Recognize that the electron transport chain uses NADH and FADH2 (produced in Glycolysis and the Citric acid cycle) to drive ATP synthesis through a proton gradient and ATP synthase.
Step 4: Compare the total ATP produced by each pathway, noting that Oxidative phosphorylation generates the majority of ATP due to the high efficiency of the electron transport chain.
Step 5: Conclude that Oxidative phosphorylation via the electron transport chain produces the greatest amount of ATP per molecule of glucose in aerobic respiration.
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