Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

4. Protein Structure

Denaturation

Biochemistry

4. Protein Structure

Denaturation

Previous problemNext problem

Struggling with Biochemistry?

Join thousands of students who trust us to help them ace their exams!Watch the first video

Multiple Choice

Proteins can be denatured by all the following except __________.

organic solvents

strong acids

heat

enzymatic hydrolysis

Previous problemNext problem

Verified step by step guidance

Understand the concept of protein denaturation: Protein denaturation refers to the process where a protein loses its native structure due to external stress or agents, such as heat, strong acids, or organic solvents. This disrupts the non-covalent interactions (e.g., hydrogen bonds, ionic bonds, hydrophobic interactions) that maintain the protein's structure.

Review the listed options: Organic solvents, strong acids, and heat are all common agents that can denature proteins by disrupting their secondary, tertiary, or quaternary structures. Enzymatic hydrolysis, however, is a different process.

Clarify enzymatic hydrolysis: Enzymatic hydrolysis involves breaking down proteins into smaller peptides or amino acids using enzymes like proteases. This is not denaturation but rather a chemical cleavage of peptide bonds, which is distinct from the structural disruption caused by denaturation.

Compare enzymatic hydrolysis to denaturation: Denaturation alters the protein's structure without breaking peptide bonds, whereas enzymatic hydrolysis breaks peptide bonds to degrade the protein into smaller components.

Conclude why enzymatic hydrolysis is the correct answer: Since enzymatic hydrolysis does not cause denaturation but instead chemically breaks down the protein, it is the exception among the listed options.