Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

3. Amino Acids

Amino Acid Configuration

Biochemistry

3. Amino Acids

Amino Acid Configuration

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Multiple Choice

Which of the following functional groups of an amino acid would be in the ionized (deprotonated) state at high pH?

Amino group (\(-NH_2\))

Side chain of glycine

Hydrogen atom attached to the alpha carbon

Carboxyl group (\(-COO^-\))

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Verified step by step guidance

Understand the concept of pH and its effect on ionization: At high pH (basic conditions), the environment has a low concentration of hydrogen ions ( ext{H}^+), which promotes deprotonation of acidic functional groups.

Identify the functional groups in an amino acid: Amino acids typically have an amino group ( ext{-NH}_2), a carboxyl group ( ext{-COOH}), a hydrogen atom attached to the alpha carbon, and a side chain (R group).

Determine the behavior of the carboxyl group ( ext{-COOH}) at high pH: The carboxyl group is acidic and tends to lose a proton ( ext{H}^+) under basic conditions, becoming ionized as ext{-COO}^-.

Analyze the amino group ( ext{-NH}_2): The amino group is basic and tends to accept a proton ( ext{H}^+) under acidic conditions, but at high pH, it remains in its neutral state ( ext{-NH}_2) and does not ionize further.

Conclude that the carboxyl group ( ext{-COO}^-) is the functional group that would be in the ionized (deprotonated) state at high pH, as it loses a proton and becomes negatively charged.