Multiple Choice
In the glycolysis pathway, what is the net amount of ATP produced per molecule of glucose converted to two molecules of pyruvate?
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Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway
Glycolysis 1
Multiple Choice
In glycolysis (from one molecule of glucose to two molecules of pyruvate), what is the net ATP yield per glucose molecule under typical aerobic conditions (counting only ATP directly produced/consumed in glycolysis, not NADH)?
A
Net ATP per glucose
B
Net ATP per glucose
C
Net ATP per glucose
D
Net ATP per glucose
Verified step by step guidance1
Identify the key stages in glycolysis where ATP is consumed and produced. Glycolysis converts one glucose molecule into two pyruvate molecules through a series of enzymatic steps.
Note that ATP is consumed in the initial energy investment phase. Specifically, 2 ATP molecules are used to phosphorylate glucose and its intermediates.
Recognize that ATP is produced in the later energy payoff phase. Here, 4 ATP molecules are generated by substrate-level phosphorylation (2 ATP per each of the two 3-carbon molecules formed).
Calculate the net ATP yield by subtracting the ATP consumed from the ATP produced: Net ATP = ATP produced - ATP consumed.
Since the problem asks only for ATP directly produced or consumed in glycolysis (excluding NADH), focus solely on these ATP values to find the net yield per glucose molecule.
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