Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

7. Enzyme Inhibition and Regulation

Enzyme Inhibition

Biochemistry

7. Enzyme Inhibition and Regulation

Enzyme Inhibition

Previous problemNext problem

Struggling with Biochemistry?

Join thousands of students who trust us to help them ace their exams!Watch the first video

Multiple Choice

Which of the following best distinguishes covalent catalysis from acid-base catalysis in enzyme mechanisms?

Covalent catalysis involves the formation of a transient covalent bond between the enzyme and substrate, whereas acid-base catalysis involves the transfer of protons to or from the substrate.

Acid-base catalysis always results in the formation of a covalent intermediate, while covalent catalysis does not.

Covalent catalysis requires metal ions as cofactors, while acid-base catalysis does not.

Both covalent catalysis and acid-base catalysis involve only non-covalent interactions between enzyme and substrate.

Previous problemNext problem

Verified step by step guidance

Step 1: Begin by understanding the two types of catalysis mentioned in the problem: covalent catalysis and acid-base catalysis. Covalent catalysis involves the formation of a transient covalent bond between the enzyme and the substrate during the reaction. Acid-base catalysis, on the other hand, involves the transfer of protons (H⁺) to or from the substrate to stabilize intermediates or facilitate the reaction.

Step 2: Analyze the first statement: 'Covalent catalysis involves the formation of a transient covalent bond between the enzyme and substrate, whereas acid-base catalysis involves the transfer of protons to or from the substrate.' This statement correctly describes the fundamental difference between the two mechanisms.

Step 3: Evaluate the second statement: 'Acid-base catalysis always results in the formation of a covalent intermediate, while covalent catalysis does not.' This is incorrect because acid-base catalysis does not necessarily involve covalent intermediates; it primarily involves proton transfer.

Step 4: Assess the third statement: 'Covalent catalysis requires metal ions as cofactors, while acid-base catalysis does not.' This is incorrect because covalent catalysis does not inherently require metal ions; metal ions may be involved in some enzyme mechanisms but are not a defining feature of covalent catalysis.

Step 5: Examine the fourth statement: 'Both covalent catalysis and acid-base catalysis involve only non-covalent interactions between enzyme and substrate.' This is incorrect because covalent catalysis explicitly involves the formation of a covalent bond between the enzyme and substrate, which is not a non-covalent interaction.