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Multiple Choice
In the context of Gibbs free energy and cellular energy coupling, how are ATP and ADP related?
A
ADP is hydrolyzed to ATP and inorganic phosphate, releasing free energy.
B
ATP and ADP have identical phosphate group numbers and differ only in their nitrogenous bases.
C
ATP is formed from ADP only by spontaneous reaction in water without any energy input or coupling.
D
ATP is hydrolyzed to ADP and inorganic phosphate (), releasing free energy that can drive endergonic reactions.
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Verified step by step guidance
1
Understand the role of ATP (adenosine triphosphate) and ADP (adenosine diphosphate) in cellular energy transfer: ATP contains three phosphate groups, while ADP contains two.
Recognize that ATP hydrolysis involves breaking the bond between the terminal phosphate group of ATP, resulting in ADP and an inorganic phosphate (P\_i).
Note that this hydrolysis reaction releases free energy (\(\u\)0394G < 0), which cells harness to drive endergonic (energy-requiring) biochemical reactions.
Understand that the reverse process, synthesizing ATP from ADP and P\_i, requires an input of energy and does not occur spontaneously in water without coupling to an energy source (e.g., cellular respiration or photosynthesis).
Summarize that ATP acts as an energy currency by cycling between ATP and ADP + P\_i, coupling exergonic and endergonic reactions in the cell.