Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

10. Lipids

Integral Membrane Proteins

Biochemistry

10. Lipids

Integral Membrane Proteins

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Multiple Choice

Which of the following statements about integral proteins is NOT correct?

They are firmly associated with the membrane.

They contain hydrophobic regions that interact with hydrophobic lipid tails.

They can be easily extracted/separated from lipid membranes by just a relatively small change in the pH.

They commonly contain α-helices or multi-stranded β-barrels.

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Verified step by step guidance

Understand the nature of integral proteins: Integral proteins are embedded within the lipid bilayer of cell membranes and are characterized by their strong association with the membrane.

Recognize the structural features of integral proteins: These proteins typically have hydrophobic regions that interact with the hydrophobic tails of the lipid molecules in the membrane, allowing them to be stably integrated into the membrane structure.

Identify the structural motifs in integral proteins: Integral proteins often contain α-helices or β-barrels, which span the membrane and contribute to their stability and function.

Consider the methods of extraction: Integral proteins are not easily extracted from membranes. They require the use of detergents or other agents that disrupt the lipid bilayer, rather than simple changes in pH, to be removed.

Evaluate the statements: Based on the understanding of integral proteins, the statement that they can be easily extracted by a small change in pH is incorrect, as it contradicts the known methods required to extract these proteins from membranes.