why-are-multiple-steps-required-to-reverse-the-action-of-pyruvate-kinase-in-gluc

Question

Why are multiple steps required to reverse the action of pyruvate kinase in gluconeogenesis?

Accepted Answer

Because the reaction is highly energetically favorable.

Answer

Because it involves a complex substrate.

Answer

Because pyruvate kinase is an irreversible enzyme.

Answer

Because it requires more ATP than other reactions.