Question 1

Which type of bond connects nucleotides in a DNA strand?

Accepted Answer

Phosphodiester bond

Question 2

The two strands of DNA run in which orientation relative to each other?

Accepted Answer

Antiparallel

Question 3

Which of the following best explains why RNA is less stable than DNA?

Accepted Answer

RNA has a 2' hydroxyl group that makes it more susceptible to hydrolysis

Question 4

If a double-stranded DNA sample contains 35% adenine, what is the percentage of guanine?

Accepted Answer

15%

Question 5

Which base pairing in DNA contributes to a higher melting temperature?

Accepted Answer

G-C base pairs

Question 6

What is the maximum light absorption wavelength for nucleic acids?

Accepted Answer

$$260\ \mathrm{nm}$$

Question 7

Which of the following is a purine base found in DNA?

Accepted Answer

Adenine

Question 8

If a DNA molecule is composed of 40% guanine, what is the percentage of cytosine?

Accepted Answer

40%

Question 9

Which statement best describes the specificity of base pairing in DNA?

Accepted Answer

A pairs with T, G pairs with C

Question 10

A DNA sample is found to have 30% thymine. What is the percentage of cytosine?

Accepted Answer

20%

Question 11

Which of the following is NOT a pyrimidine base in DNA?

Accepted Answer

Adenine

Question 12

What percentage of double-stranded DNA is made up of purines?

Accepted Answer

50%

Question 13

Which chemical group is responsible for the increased hydrolysis susceptibility of RNA?

Accepted Answer

2' hydroxyl group

Question 14

If a DNA sample has 15% cytosine, what is the percentage of thymine?

Accepted Answer

35%

Question 15

Which of the following statements about DNA structure is correct?

Accepted Answer

The strands are antiparallel and held together by hydrogen bonds between bases

Question 16

A DNA molecule is analyzed and found to have 22% guanine. What is the percentage of adenine?

Accepted Answer

28%

Question 17

Which of the following would increase the melting temperature of a DNA molecule?

Accepted Answer

Increasing the number of G-C base pairs

Question 18

Which of the following is true regarding the absorption of nucleic acids?

Accepted Answer

Nucleic acids absorb maximally at 260 nm

Question 19

Which of the following is a consequence of the antiparallel nature of DNA strands?

Accepted Answer

Base pairing is possible due to complementary orientation

Question 20

If a DNA sample contains 20% adenine, what is the percentage of guanine?

Accepted Answer

30%

Nucleic Acids: Structure and Properties

Study Guide - Practice Questions