Question 1

Which of the following best describes the relationship between D-glucose and D-mannose?

Accepted Answer

They are epimers.

Question 2

How many stereoisomers are possible for a monosaccharide with 4 chiral centers?

Accepted Answer

$$2^4 = 16$

Question 3

Which of the following statements about enantiomers is correct?

Accepted Answer

They are non-superimposable mirror images.

Question 4

Two sugars that differ only in the configuration around one specific carbon atom are called:

Accepted Answer

Epimers

Question 5

Given a monosaccharide with the Fischer projection shown, which term best describes the relationship between D-glucose and L-glucose?

Accepted Answer

Enantiomers

Question 6

Which of the following is NOT a characteristic of diastereomers?

Accepted Answer

They are non-superimposable mirror images.

Question 7

If a sugar has 3 chiral centers, how many stereoisomers are possible?

Accepted Answer

$$2^3 = 8$

Question 8

Which of the following pairs are enantiomers?

Accepted Answer

D-glucose and L-glucose

Question 9

Which of the following best describes constitutional isomers?

Accepted Answer

They have the same molecular formula but different connectivity.

Question 10

Which of the following is true about the Fischer projection of monosaccharides?

Accepted Answer

Horizontal lines represent bonds coming out of the plane.

Question 11

Which term best describes the relationship between D-mannose and L-mannose?

Accepted Answer

Same molecule

Question 12

Which of the following is a C-4 epimer of D-glucose?

Accepted Answer

D-galactose

Question 13

Which of the following statements is correct regarding the number of stereoisomers for a sugar with $$n$$ chiral centers?

Accepted Answer

The number of stereoisomers is $$2^n.$$

Question 14

Which of the following best describes the relationship between D-glucose and D-galactose?

Accepted Answer

They are C-4 epimers.

Question 15

Which of the following is true about enantiomers?

Accepted Answer

They have identical physical properties except for the direction in which they rotate plane-polarized light.

Question 16

Which of the following is NOT a stereoisomer of D-glucose?

Accepted Answer

D-fructose

Question 17

Which of the following best describes the relationship between D-glucose and D-fructose?

Accepted Answer

They are constitutional isomers.

Question 18

Which of the following is a property of diastereomers?

Accepted Answer

They have different physical properties.

Question 19

Which of the following is true about the number of stereoisomers for a sugar with 5 chiral centers?

Accepted Answer

$$2^5 = 32$

Question 20

Which of the following best describes the relationship between D-glucose and D-mannose?

Accepted Answer

They are C-2 epimers.

Stereochemistry of Monosaccharides: Isomerism and Epimers

Study Guide - Practice Questions