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Multiple Choice
Translation termination occurs when a ribosome interacts with which of the following structures?
A
tRNA molecule
B
Start codon
C
Amino acid
D
Stop codon
Verified step by step guidance
1
Understand the process of translation: Translation is the process by which ribosomes synthesize proteins using mRNA as a template. It involves initiation, elongation, and termination phases.
Identify the role of codons: Codons are sequences of three nucleotides on the mRNA that correspond to specific amino acids or signal termination. The start codon (AUG) signals the beginning of translation, while stop codons signal the end.
Recognize the stop codons: In the genetic code, there are three stop codons (UAA, UAG, UGA) that do not code for any amino acids. Instead, they signal the ribosome to terminate translation.
Explain the interaction: During translation termination, the ribosome encounters a stop codon on the mRNA. This does not correspond to any tRNA molecule carrying an amino acid, but instead, it recruits release factors.
Conclude the process: The release factors bind to the stop codon, prompting the ribosome to release the newly synthesized polypeptide chain and disassemble, effectively ending the translation process.