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Multiple Choice
Which model correctly represents the polarity of double-stranded DNA?
A
The strands have no specific polarity.
B
Both strands run in a 3' to 5' direction.
C
One strand runs 5' to 3' and the other runs 3' to 5'.
D
Both strands run in a 5' to 3' direction.
Verified step by step guidance
1
Understand the structure of DNA: DNA is a double-stranded molecule composed of nucleotides. Each strand has a sugar-phosphate backbone with a directionality determined by the orientation of the sugar molecules (deoxyribose).
Learn about the 5' and 3' ends: The 5' end of a DNA strand has a phosphate group attached to the fifth carbon of the sugar, while the 3' end has a hydroxyl group attached to the third carbon of the sugar. This establishes the polarity of the strand.
Recognize the antiparallel nature of DNA: In double-stranded DNA, the two strands run in opposite directions. One strand runs in the 5' to 3' direction, while the complementary strand runs in the 3' to 5' direction. This arrangement is referred to as antiparallel polarity.
Understand base pairing: The strands are held together by hydrogen bonds between complementary bases (adenine pairs with thymine, and cytosine pairs with guanine). The antiparallel orientation ensures proper alignment for base pairing.
Conclude the correct model: Based on the structure and polarity of DNA, the correct representation is that one strand runs 5' to 3' and the other runs 3' to 5'. This antiparallel arrangement is a fundamental characteristic of double-stranded DNA.