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Multiple Choice
During glycolysis, which molecule is oxidized and broken down to produce pyruvate?
A
Glycogen
B
Glucose
C
Lactate
D
Fructose
Verified step by step guidance
1
Understand the process of glycolysis: Glycolysis is the metabolic pathway where glucose is broken down into pyruvate, producing ATP and NADH in the process.
Identify the molecule that serves as the primary substrate for glycolysis: Glucose is the molecule that is oxidized and broken down during glycolysis.
Clarify why glucose is the correct answer: Glycogen is a storage form of glucose and must be broken down into glucose before entering glycolysis. Lactate is a product of anaerobic metabolism, not a substrate for glycolysis. Fructose can enter glycolysis but only after being converted into intermediates like fructose-6-phosphate.
Explain the chemical transformation: During glycolysis, glucose (C₆H₁₂O₆) is phosphorylated and split into two 3-carbon molecules, which are further oxidized to form pyruvate (C₃H₄O₃).
Highlight the importance of glucose in glycolysis: Glucose is the universal energy source for cells and is the molecule specifically oxidized in glycolysis to generate energy in the form of ATP.