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Multiple Choice
In which phase of mitosis do sister chromatids separate?
A
Metaphase
B
Anaphase
C
Prophase
D
Telophase
Verified step by step guidance
1
Understand the process of mitosis, which is the division of a single cell into two genetically identical daughter cells. Mitosis consists of several phases: prophase, metaphase, anaphase, and telophase.
Recall that during metaphase, the chromosomes align at the metaphase plate, which is the equatorial plane of the cell. The sister chromatids are attached to spindle fibers from opposite poles.
Identify that anaphase is the phase where the sister chromatids are pulled apart. The centromeres split, and the spindle fibers shorten, pulling the chromatids toward opposite poles of the cell.
Recognize that in prophase, the chromosomes condense and become visible, but the sister chromatids are not yet separated.
Note that in telophase, the separated chromatids reach the opposite poles, and the cell begins to divide, but the separation of sister chromatids has already occurred in anaphase.