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Multiple Choice
Which of the following signifies translation termination?
A
The ribosome reaches a stop codon on the mRNA
B
A tRNA carrying methionine binds to the ribosome
C
The ribosome binds to the start codon on the mRNA
D
The ribosome detaches from the mRNA after a release factor binds
Verified step by step guidance
1
Understand the process of translation: Translation is the process by which ribosomes synthesize proteins using mRNA as a template. It involves initiation, elongation, and termination phases.
Identify the role of stop codons: In the termination phase, the ribosome encounters a stop codon on the mRNA. Stop codons are specific sequences (UAA, UAG, UGA) that signal the end of protein synthesis.
Recognize the function of release factors: When the ribosome reaches a stop codon, release factors bind to the ribosome. These proteins facilitate the release of the newly synthesized polypeptide chain from the ribosome.
Understand ribosome detachment: After the release factor binds, the ribosome detaches from the mRNA, completing the translation process.
Connect the concepts: The correct answer is that translation termination is signified by the ribosome reaching a stop codon on the mRNA, leading to the binding of a release factor and subsequent detachment of the ribosome.