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Multiple Choice
Which of the following statements regarding translation elongation is true?
A
Peptide bonds are formed at the E site of the ribosome.
B
Elongation factors are not required during translation elongation.
C
Aminoacyl-tRNA binds to the A site of the ribosome.
D
The ribosome moves along the mRNA in the 3' to 5' direction.
Verified step by step guidance
1
Understand the process of translation elongation, which is a phase in protein synthesis where amino acids are sequentially added to a growing polypeptide chain.
Identify the role of the ribosome during translation elongation. The ribosome has three sites: A (aminoacyl), P (peptidyl), and E (exit).
Recognize that aminoacyl-tRNA binds to the A site of the ribosome, where it brings a new amino acid to be added to the polypeptide chain.
Clarify that peptide bonds are formed at the P site, not the E site, as the growing polypeptide chain is transferred from the tRNA in the P site to the tRNA in the A site.
Note that elongation factors are required during translation elongation to facilitate the binding of tRNA to the ribosome and the movement of the ribosome along the mRNA, which occurs in the 5' to 3' direction.