Multiple Choice
In the process of translation, what would you expect to find bound to the stop codon at the A site of the ribosome?
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15. Gene Expression
Steps of Translation
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Which step occurs in the P site of the ribosome during translation?
A
Codon recognition
B
mRNA binding
C
Peptide bond formation
D
tRNA exit
Verified step by step guidance1
Understand the role of the ribosome in translation: The ribosome is the molecular machine that facilitates the synthesis of proteins by translating mRNA into a polypeptide chain.
Identify the sites within the ribosome: The ribosome has three key sites known as the A (aminoacyl), P (peptidyl), and E (exit) sites, each playing a distinct role in translation.
Focus on the P site: The P site is where the growing polypeptide chain is held. It is crucial for peptide bond formation, which links amino acids together.
Recognize the process of peptide bond formation: During translation, the ribosome catalyzes the formation of peptide bonds between the amino acids carried by tRNAs. This occurs in the P site, where the polypeptide chain is transferred from the tRNA in the P site to the tRNA in the A site.
Differentiate between the steps: Codon recognition occurs in the A site, mRNA binding is part of the initiation process, and tRNA exit happens at the E site. Peptide bond formation is the key step occurring in the P site.
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