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Multiple Choice
What is the role of the enzyme primase in DNA replication?
A
It synthesizes RNA primers needed to start DNA synthesis.
B
It unwinds the DNA double helix.
C
It seals gaps between Okazaki fragments.
D
It adds nucleotides to the growing DNA strand.
Verified step by step guidance
1
Understand the process of DNA replication: DNA replication is the process by which a cell duplicates its DNA, ensuring that each daughter cell receives an exact copy of the genetic material.
Identify the role of primase: Primase is an enzyme that synthesizes short RNA sequences called primers. These primers are necessary for DNA polymerase to start synthesizing the new DNA strand.
Recognize the importance of RNA primers: DNA polymerase cannot initiate the synthesis of a new DNA strand on its own. It requires a primer to provide a starting point for adding nucleotides.
Differentiate primase from other enzymes: Primase is distinct from other enzymes involved in DNA replication, such as helicase (which unwinds the DNA double helix) and DNA ligase (which seals gaps between Okazaki fragments).
Clarify the sequence of events: During DNA replication, primase synthesizes RNA primers, which are then extended by DNA polymerase to form the new DNA strand. This is crucial for the replication of both the leading and lagging strands.