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Multiple Choice
To which part of a DNA molecule are nucleotides added during replication?
A
Middle of the strand
B
Both ends simultaneously
C
3' end
D
5' end
Verified step by step guidance
1
Understand the structure of a DNA molecule: DNA is composed of two strands forming a double helix, with each strand having a directionality, indicated by 5' (five prime) and 3' (three prime) ends.
Learn about DNA replication: During replication, DNA polymerase enzymes synthesize new DNA strands by adding nucleotides to the existing strand.
Recognize the directionality of DNA synthesis: DNA polymerase can only add nucleotides to the 3' end of the growing strand, meaning replication proceeds in a 5' to 3' direction.
Consider the implications of this directionality: Since nucleotides are added to the 3' end, the newly synthesized strand grows in the opposite direction to the template strand.
Apply this knowledge to the problem: When asked where nucleotides are added during replication, the correct answer is the 3' end of the DNA strand.