Join thousands of students who trust us to help them ace their exams!Watch the first video
Multiple Choice
Which of the following helps explain the remarkably high fidelity of DNA replication?
A
Lack of repair mechanisms
B
High mutation rate
C
Proofreading by DNA polymerase
D
Random incorporation of nucleotides
Verified step by step guidance
1
Understand the concept of DNA replication fidelity: DNA replication fidelity refers to the accuracy with which DNA is copied during cell division. High fidelity ensures that genetic information is accurately passed on to daughter cells.
Learn about the role of DNA polymerase: DNA polymerase is an enzyme responsible for synthesizing new DNA strands by adding nucleotides to a growing chain. It plays a crucial role in ensuring replication accuracy.
Explore the proofreading function of DNA polymerase: DNA polymerase has a proofreading ability, which means it can identify and correct errors during DNA synthesis. This function significantly contributes to the high fidelity of DNA replication.
Consider the impact of repair mechanisms: While repair mechanisms are important for correcting errors post-replication, the proofreading function of DNA polymerase is a primary factor during the replication process itself.
Evaluate the options given: Lack of repair mechanisms and high mutation rate would decrease fidelity, while random incorporation of nucleotides would lead to errors. Proofreading by DNA polymerase is the correct answer as it directly enhances replication fidelity.