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Multiple Choice
Which of the following statements is true of DNA synthesis?
A
DNA synthesis occurs in the 5' to 3' direction.
B
DNA synthesis is initiated at the telomeres.
C
DNA synthesis does not require a primer.
D
DNA synthesis occurs in the 3' to 5' direction.
Verified step by step guidance
1
Understand the directionality of DNA synthesis: DNA polymerases synthesize new DNA strands by adding nucleotides to the 3' end of the growing strand, thus DNA synthesis occurs in the 5' to 3' direction.
Recognize the role of primers in DNA synthesis: DNA synthesis requires a primer, which is a short RNA sequence that provides a starting point for DNA polymerase to begin synthesis.
Identify the initiation sites of DNA synthesis: DNA synthesis is initiated at origins of replication, not at telomeres. Telomeres are the ends of chromosomes and are involved in protecting the DNA from degradation.
Clarify the incorrect directionality statement: DNA synthesis does not occur in the 3' to 5' direction. This is a common misconception; DNA polymerase can only add nucleotides to the 3' end of the strand.
Evaluate the statements: Based on the understanding of DNA synthesis directionality, primer requirement, and initiation sites, determine which statement accurately describes DNA synthesis.