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Multiple Choice
Why does a graph of the membrane potential of living pacemaker cells never demonstrate a flat line?
A
Because pacemaker cells continuously undergo spontaneous depolarization, preventing a stable resting membrane potential.
B
Because the membrane potential is constantly stabilized by sodium-potassium pumps.
C
Because pacemaker cells lack ion channels required for membrane potential changes.
D
Because pacemaker cells are incapable of generating action potentials.
Verified step by step guidance
1
Understand the role of pacemaker cells: Pacemaker cells are specialized cells found in the heart that generate rhythmic electrical impulses to regulate the heartbeat. They are unique because they do not have a stable resting membrane potential.
Identify the key characteristic of pacemaker cells: Unlike other cells, pacemaker cells undergo spontaneous depolarization due to the activity of specific ion channels, such as 'funny' channels (If) that allow a slow influx of sodium ions.
Explain the spontaneous depolarization process: The 'funny' channels open during hyperpolarization, allowing sodium ions to enter the cell. This gradually increases the membrane potential until it reaches the threshold for an action potential.
Discuss why the graph never shows a flat line: Since pacemaker cells continuously undergo cycles of depolarization and repolarization, the membrane potential is always changing. This prevents the graph from showing a flat line, as there is no stable resting state.
Clarify the incorrect options: Pacemaker cells do not lack ion channels; they rely on specific channels for their function. They are capable of generating action potentials, and while sodium-potassium pumps help maintain ion gradients, they do not stabilize the membrane potential in pacemaker cells.