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Multiple Choice
In which mitotic phase are the sister chromatids separated and pulled to opposite poles?
A
Anaphase
B
Prophase
C
Telophase
D
Metaphase
Verified step by step guidance
1
Understand the process of mitosis, which is the division of a single cell into two genetically identical daughter cells. Mitosis consists of several phases: prophase, metaphase, anaphase, and telophase.
Recall that during prophase, the chromatin condenses into visible chromosomes, and the mitotic spindle begins to form. The nuclear envelope breaks down, but sister chromatids are not yet separated.
In metaphase, the chromosomes align at the cell's equatorial plane, known as the metaphase plate. The sister chromatids are attached to spindle fibers from opposite poles, but they remain together at this stage.
During anaphase, the centromeres split, and the sister chromatids are separated. The spindle fibers shorten, pulling the sister chromatids toward opposite poles of the cell. This is the phase where separation occurs.
In telophase, the separated chromatids, now individual chromosomes, reach the opposite poles. The nuclear envelope re-forms around each set of chromosomes, and the chromosomes begin to de-condense, marking the end of mitosis.