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Multiple Choice
Which of the following is the first event to take place in translation in eukaryotes?
A
The tRNA carrying methionine binds to the start codon
B
The ribosome reaches a stop codon
C
The small ribosomal subunit binds to the mRNA
D
The large ribosomal subunit joins the complex
Verified step by step guidance
1
Translation is the process by which ribosomes synthesize proteins using mRNA as a template. In eukaryotes, this process involves several key steps.
The first event in translation is the binding of the small ribosomal subunit to the mRNA. This occurs at the 5' cap of the mRNA, which helps the ribosome recognize and bind to the mRNA strand.
Once the small ribosomal subunit is bound to the mRNA, it scans along the mRNA to find the start codon, which is typically AUG. This codon signals the beginning of the protein-coding sequence.
The tRNA carrying methionine then binds to the start codon. Methionine is the first amino acid in the newly synthesized protein, and its tRNA is known as the initiator tRNA.
Finally, the large ribosomal subunit joins the complex, completing the formation of the functional ribosome. This allows translation to proceed, with the ribosome moving along the mRNA and synthesizing the protein.