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Multiple Choice
Which of the following is the best example of negative feedback?
A
Regulation of blood glucose levels by insulin and glucagon
B
Activation of pepsinogen to pepsin in the stomach
C
Release of oxytocin to intensify uterine contractions during childbirth
D
Blood clotting cascade amplifying the response to injury
Verified step by step guidance
1
Step 1: Understand the concept of negative feedback. Negative feedback is a regulatory mechanism in which a change in a physiological variable triggers a response that counteracts the initial change, maintaining homeostasis.
Step 2: Analyze the first option: Regulation of blood glucose levels by insulin and glucagon. Insulin lowers blood glucose levels when they are high, while glucagon raises blood glucose levels when they are low. This is a classic example of negative feedback because the system works to restore balance.
Step 3: Analyze the second option: Activation of pepsinogen to pepsin in the stomach. This is not an example of negative feedback; it is a biochemical activation process that does not involve counteracting a change.
Step 4: Analyze the third option: Release of oxytocin to intensify uterine contractions during childbirth. This is an example of positive feedback, where the response amplifies the initial stimulus rather than counteracting it.
Step 5: Analyze the fourth option: Blood clotting cascade amplifying the response to injury. This is another example of positive feedback, as the cascade amplifies the clotting process to seal the injury.