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Multiple Choice
DNA polymerase can only synthesize DNA in which direction?
A
3' to 3'
B
5' to 5'
C
5' to 3'
D
3' to 5'
Verified step by step guidance
1
Understand the structure of a DNA strand: DNA strands have a directionality, with one end having a free 5' phosphate group and the other end having a free 3' hydroxyl group.
Recognize the role of DNA polymerase: DNA polymerase is the enzyme responsible for synthesizing new DNA strands by adding nucleotides to a pre-existing chain.
Identify the direction of synthesis: DNA polymerase can only add new nucleotides to the 3' end of the growing DNA strand, meaning it synthesizes DNA in the 5' to 3' direction.
Consider the template strand: The template strand is read in the 3' to 5' direction by DNA polymerase, allowing the new strand to be synthesized in the 5' to 3' direction.
Conclude the correct synthesis direction: Based on the enzyme's function and the structure of DNA, DNA polymerase synthesizes DNA in the 5' to 3' direction.