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Multiple Choice
Which structure is responsible for separating sister chromatids during anaphase of mitosis?
A
Spindle fibers (microtubules)
B
Golgi apparatus
C
Mitochondria
D
Nucleolus
Verified step by step guidance
1
Understand the context of the question: The problem is asking about the structure responsible for separating sister chromatids during anaphase of mitosis, which is a key phase in cell division.
Recall the process of mitosis: During anaphase, sister chromatids are pulled apart to opposite poles of the cell. This ensures that each daughter cell receives an identical set of chromosomes.
Identify the structures involved: Spindle fibers, composed of microtubules, are the structures that attach to the centromeres of sister chromatids via protein complexes called kinetochores.
Explain the mechanism: Spindle fibers shorten by depolymerizing their microtubules, pulling the sister chromatids apart toward opposite poles of the cell. This movement is facilitated by motor proteins such as dynein and kinesin.
Eliminate incorrect options: The Golgi apparatus, mitochondria, and nucleolus are not involved in separating sister chromatids during mitosis. The correct structure is spindle fibers (microtubules).