Multiple Choice
In the regulation of gene expression, how do enhancers differ from promoters?
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16. Regulation of Expression
Introduction to Regulation of Gene Expression
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How does NF-κB induce gene expression?
A
By binding to specific DNA sequences in the promoter region of target genes
B
By degrading mRNA molecules to prevent translation
C
By inhibiting RNA polymerase activity
D
By directly interacting with ribosomes to enhance translation
Verified step by step guidance1
Understand the role of NF-κB: NF-κB is a protein complex that functions as a transcription factor, meaning it helps regulate the expression of specific genes.
Identify the mechanism of action: NF-κB induces gene expression by binding to specific DNA sequences known as κB sites, which are located in the promoter regions of target genes.
Explore the promoter region: The promoter region is a sequence of DNA that initiates transcription of a particular gene. NF-κB binding to this region facilitates the recruitment of RNA polymerase, which is essential for transcription.
Clarify the transcription process: Once NF-κB is bound to the DNA, it helps recruit other proteins that form the transcription machinery, leading to the synthesis of mRNA from the DNA template.
Differentiate from other options: NF-κB does not degrade mRNA, inhibit RNA polymerase, or directly interact with ribosomes. Its primary role is to enhance transcription by binding to DNA in the promoter region.
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