Join thousands of students who trust us to help them ace their exams!Watch the first video
Multiple Choice
Which of these could lead to the conversion of a proto-oncogene into an oncogene?
A
Chromosome deletion
B
DNA repair
C
Gene amplification
D
Increased apoptosis
Verified step by step guidance
1
Understand the role of proto-oncogenes: Proto-oncogenes are normal genes that, when mutated or expressed at high levels, can become oncogenes and contribute to cancer development.
Identify the mechanisms that can convert a proto-oncogene into an oncogene: This can occur through mutations, chromosomal rearrangements, or changes in gene expression levels.
Focus on gene amplification: Gene amplification refers to an increase in the number of copies of a gene, leading to overexpression of the gene product.
Consider how gene amplification affects proto-oncogenes: When a proto-oncogene is amplified, it can lead to excessive production of proteins that promote cell division and survival, potentially leading to cancer.
Evaluate the other options: Chromosome deletion typically results in loss of gene function, DNA repair maintains genomic integrity, and increased apoptosis leads to cell death, none of which directly convert proto-oncogenes into oncogenes.