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Multiple Choice
What is the source of the yellow pigment urochrome found in human urine?
A
Oxidation of melanin in the skin
B
Breakdown of hemoglobin from red blood cells
C
Metabolism of bilirubin in the liver
D
Digestion of dietary carotenoids
Verified step by step guidance
1
Understand the context of the question: The yellow pigment urochrome in human urine is a result of metabolic processes in the body. The question asks about the specific source of this pigment.
Recall the biological process of hemoglobin breakdown: Hemoglobin, found in red blood cells, is broken down when the cells reach the end of their lifespan. This process occurs in the spleen and liver.
Learn about bilirubin metabolism: During hemoglobin breakdown, heme is converted into biliverdin and then into bilirubin. Bilirubin is transported to the liver, where it undergoes further metabolism.
Connect bilirubin metabolism to urochrome production: Bilirubin is eventually excreted into the intestines and further metabolized by gut bacteria. Some of its byproducts, such as urobilinogen, are reabsorbed into the bloodstream and filtered by the kidneys, where they contribute to the formation of urochrome.
Eliminate incorrect options: Oxidation of melanin in the skin, digestion of dietary carotenoids, and other processes do not directly contribute to the production of urochrome. The correct source is the breakdown of hemoglobin from red blood cells and subsequent metabolism of bilirubin in the liver.