Join thousands of students who trust us to help them ace their exams!Watch the first video
Multiple Choice
Why must primase be used before DNA polymerase during DNA replication?
A
Primase unwinds the DNA double helix to allow replication to begin.
B
Primase adds nucleotides to the growing DNA strand in the 5' to 3' direction.
C
Primase repairs mismatched bases during DNA replication.
D
Primase synthesizes a short RNA primer that provides a starting point for DNA polymerase.
Verified step by step guidance
1
Understand the role of primase in DNA replication: Primase is an enzyme that synthesizes a short RNA primer, which is essential for initiating DNA synthesis.
Recognize the function of DNA polymerase: DNA polymerase is responsible for adding nucleotides to the growing DNA strand, but it requires a primer to start the synthesis process.
Identify the sequence of events: During DNA replication, primase acts first to create the RNA primer, which provides a free 3'-OH group for DNA polymerase to begin adding DNA nucleotides.
Clarify why primase is necessary: DNA polymerase cannot initiate the synthesis of a new DNA strand on its own; it can only add nucleotides to an existing strand or primer.
Summarize the importance of the primer: The RNA primer synthesized by primase is crucial because it allows DNA polymerase to perform its function effectively, ensuring accurate and efficient DNA replication.