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Multiple Choice
What site on the ribosome is primarily responsible for holding the growing polypeptide during translation?
A
P site
B
E site
C
A site
D
R site
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Verified step by step guidance
1
Understand the process of translation, which is the synthesis of proteins from mRNA. This occurs in the ribosome, which has three key sites: A site, P site, and E site.
Learn the function of each site: The A site (Aminoacyl site) is where the incoming tRNA carrying an amino acid binds. The P site (Peptidyl site) holds the tRNA carrying the growing polypeptide chain. The E site (Exit site) is where the tRNA exits after its amino acid has been added to the chain.
Focus on the P site: During translation, the P site is crucial because it holds the tRNA that carries the growing polypeptide chain. This is where peptide bonds are formed between amino acids.
Consider the role of the ribosome: The ribosome facilitates the binding of tRNA to the mRNA and catalyzes the formation of peptide bonds, ensuring the polypeptide chain grows correctly.
Review the options given: The P site is responsible for holding the growing polypeptide, while the A site and E site have different roles. The R site is not a recognized site in the ribosome.