Multiple Choice
Which of the following statements applies to frameshift mutations?
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15. Gene Expression
Mutations
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Which statement best describes how the sickle cell gene mutation can affect an organism?
A
It results in the production of excess hemoglobin, improving oxygen transport.
B
It causes red blood cells to become crescent-shaped, leading to various health complications.
C
It enhances the immune system's ability to fight off infections.
D
It leads to the complete absence of red blood cells in the bloodstream.
Verified step by step guidance1
Understand that the sickle cell gene mutation affects the hemoglobin protein in red blood cells.
Recognize that normal hemoglobin allows red blood cells to maintain a flexible, disc shape, which is essential for efficient oxygen transport.
The mutation causes hemoglobin to form abnormal structures, leading to red blood cells becoming rigid and crescent-shaped, known as sickle cells.
These sickle-shaped cells can block blood flow in small vessels, causing pain and potential organ damage, which are the health complications associated with sickle cell disease.
Note that the mutation does not result in excess hemoglobin, enhanced immune function, or absence of red blood cells, but rather in the deformation of red blood cells.
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