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Multiple Choice
Which ion diffuses into the synaptic knob, resulting in the release of a neurotransmitter?
A
Calcium ion ($\mathrm{Ca^{2+}}$)
B
Sodium ion ($\mathrm{Na^+}$)
C
Chloride ion ($\mathrm{Cl^-}$)
D
Potassium ion ($\mathrm{K^+}$)
Verified step by step guidance
1
Step 1: Understand the context of the problem. The synaptic knob is the terminal end of a neuron where neurotransmitters are released into the synaptic cleft to communicate with the next cell.
Step 2: Recall the process of neurotransmitter release. When an action potential reaches the synaptic knob, it triggers the opening of voltage-gated ion channels.
Step 3: Identify the specific ion involved. Voltage-gated calcium channels open, allowing calcium ions ($\mathrm{Ca^{2+}}$) to diffuse into the synaptic knob.
Step 4: Explain the role of calcium ions ($\mathrm{Ca^{2+}}$). The influx of calcium ions signals vesicles containing neurotransmitters to fuse with the membrane and release their contents into the synaptic cleft.
Step 5: Compare the other ions listed. Sodium ions ($\mathrm{Na^+}$), chloride ions ($\mathrm{Cl^-}$), and potassium ions ($\mathrm{K^+}$) play roles in other cellular processes but are not directly responsible for triggering neurotransmitter release in this context.