Multiple Choice
Cell-mediated immunity differs from humoral immunity in that _____.
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41. Immune System
Immune System
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Which of the following would be unlikely to cause a cell-mediated immune response?
A
A bacterial toxin circulating in the bloodstream
B
A virus-infected cell presenting antigens on its surface
C
A cancer cell displaying abnormal proteins
D
A transplanted organ with foreign MHC molecules
Verified step by step guidance1
Understand the concept of cell-mediated immune response: This type of immune response involves T cells (specifically cytotoxic T cells) targeting and destroying infected cells, cancer cells, or foreign cells. It does not directly target free-floating pathogens or toxins in the bloodstream.
Analyze the bacterial toxin circulating in the bloodstream: Bacterial toxins are free-floating molecules and are typically addressed by the humoral immune response, which involves B cells and antibodies. This makes it unlikely to trigger a cell-mediated immune response.
Examine the virus-infected cell presenting antigens: Virus-infected cells display viral antigens on their surface, which are recognized by cytotoxic T cells. This is a classic example of a cell-mediated immune response.
Consider the cancer cell displaying abnormal proteins: Cancer cells often produce abnormal proteins that can be presented on their surface. These abnormal proteins can be recognized by cytotoxic T cells, triggering a cell-mediated immune response.
Evaluate the transplanted organ with foreign MHC molecules: Foreign MHC molecules on transplanted organs are recognized as non-self by the immune system, leading to a cell-mediated immune response involving T cells attacking the transplanted tissue.
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