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Multiple Choice
Cell-mediated immunity differs from humoral immunity in that _____.
A
it is responsible for the allergic response
B
it is effective only against extracellular pathogens
C
it relies on the production of antibodies to neutralize pathogens
D
it primarily involves T lymphocytes rather than B lymphocytes
Verified step by step guidance
1
Understand the two main branches of the adaptive immune system: humoral immunity and cell-mediated immunity. Humoral immunity primarily involves B lymphocytes (B cells) and the production of antibodies to neutralize extracellular pathogens, while cell-mediated immunity primarily involves T lymphocytes (T cells) and targets intracellular pathogens.
Recognize that cell-mediated immunity is responsible for defending against pathogens that reside inside host cells, such as viruses and some bacteria, by directly attacking infected cells or activating other immune cells.
Note that T lymphocytes (T cells) are the key players in cell-mediated immunity. These include cytotoxic T cells (which kill infected cells) and helper T cells (which assist in activating other immune cells).
Contrast this with humoral immunity, which relies on B lymphocytes to produce antibodies that bind to antigens on the surface of pathogens, marking them for destruction or neutralization. This process is effective against extracellular pathogens.
Conclude that the correct answer is: 'it primarily involves T lymphocytes rather than B lymphocytes,' as this is the defining characteristic of cell-mediated immunity compared to humoral immunity.