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Multiple Choice
Which of the following steps in glycolysis result in the production of ATP?
A
Conversion of glucose to glucose-6-phosphate
B
Conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate
C
Conversion of phosphoenolpyruvate (PEP) to pyruvate
D
Conversion of fructose-6-phosphate to fructose-1,6-bisphosphate
Verified step by step guidance
1
Step 1: Understand the process of glycolysis, which is the metabolic pathway that breaks down glucose into pyruvate, producing ATP and NADH in the process.
Step 2: Recall that ATP is produced during glycolysis in specific steps known as substrate-level phosphorylation. This occurs when a phosphate group is directly transferred from a substrate molecule to ADP, forming ATP.
Step 3: Analyze the given steps in the problem. The conversion of glucose to glucose-6-phosphate and fructose-6-phosphate to fructose-1,6-bisphosphate involve the use of ATP, not its production. These are energy investment steps.
Step 4: Focus on the steps where ATP is produced. The conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate and the conversion of phosphoenolpyruvate (PEP) to pyruvate are substrate-level phosphorylation steps, resulting in the production of ATP.
Step 5: Summarize that ATP is produced during glycolysis specifically in the steps involving the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate and phosphoenolpyruvate (PEP) to pyruvate. These are key energy-yielding steps in the pathway.