Join thousands of students who trust us to help them ace their exams!Watch the first video
Multiple Choice
Which of the following correctly labels the key components involved in the activation of a helper T cell by a dendritic cell?
A
MHC class I on dendritic cell, antigen peptide, B cell receptor (BCR) on helper T cell, and CD8 co-receptor
B
MHC class II on helper T cell, antigen peptide, T cell receptor (TCR) on dendritic cell, and CD8 co-receptor
C
MHC class II on dendritic cell, antigen peptide, T cell receptor (TCR) on helper T cell, and CD4 co-receptor
D
MHC class I on dendritic cell, antigen peptide, T cell receptor (TCR) on helper T cell, and CD4 co-receptor
Verified step by step guidance
1
Step 1: Understand the context of the problem. Helper T cells are activated by antigen-presenting cells (APCs), such as dendritic cells, through a process involving specific molecular interactions. These interactions are crucial for initiating an immune response.
Step 2: Recall the role of MHC molecules. Major Histocompatibility Complex (MHC) molecules are proteins on the surface of APCs that present antigen peptides to T cells. MHC class II molecules are specifically involved in presenting antigens to helper T cells.
Step 3: Identify the components on the helper T cell. Helper T cells have T cell receptors (TCRs) that recognize the antigen peptide presented by MHC class II molecules. Additionally, the CD4 co-receptor on helper T cells stabilizes the interaction with MHC class II molecules.
Step 4: Eliminate incorrect options. For example, MHC class I molecules are involved in presenting antigens to cytotoxic T cells, not helper T cells. Similarly, CD8 co-receptors are associated with cytotoxic T cells, not helper T cells.
Step 5: Confirm the correct labeling. The correct components involved in the activation of a helper T cell by a dendritic cell are: MHC class II on the dendritic cell, antigen peptide, T cell receptor (TCR) on the helper T cell, and CD4 co-receptor.