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Multiple Choice
Which of the following best describes the role of a second messenger in cell signaling pathways?
A
It relays a signal from a receptor on the cell surface to target molecules inside the cell.
B
It directly phosphorylates proteins in the nucleus.
C
It acts as the primary ligand that binds to the receptor.
D
It transports signaling molecules between different cells.
Verified step by step guidance
1
Step 1: Understand the concept of cell signaling pathways. Cell signaling involves communication between cells using signaling molecules. These molecules bind to receptors on the cell surface, initiating a cascade of events inside the cell.
Step 2: Define the role of a second messenger. A second messenger is a small molecule or ion that relays signals from the receptor (located on the cell surface) to target molecules inside the cell, amplifying the signal and triggering specific cellular responses.
Step 3: Eliminate incorrect options. For example, second messengers do not act as primary ligands (the molecules that bind directly to receptors), nor do they transport signaling molecules between cells. They also do not directly phosphorylate proteins in the nucleus; this is typically done by kinases activated later in the signaling pathway.
Step 4: Focus on the correct description. The second messenger's role is to relay and amplify the signal from the receptor to intracellular targets, ensuring the signal reaches the appropriate molecules inside the cell to elicit a response.
Step 5: Relate this concept to examples. Common second messengers include cyclic AMP (cAMP), calcium ions (Ca²⁺), and inositol triphosphate (IP₃). These molecules play critical roles in various signaling pathways, such as those regulating metabolism, gene expression, and cell growth.